Abstract

The Role of Bacteria, Probiotics and Diet in Irritable Bowel Syndrome

Harper A1, Naghibi MM2, Garcha D3. Foods. 2018 Jan 26;7(2). pii: E13. doi: 10.3390/foods7020013.
 
     

Author information

1 Protexin, Medical Affairs, Probiotics International Ltd., Lopen Head, Somerset TA13 5JH, UK. ashton.harper@protexin.com.

2 Protexin, Medical Affairs, Probiotics International Ltd., Lopen Head, Somerset TA13 5JH, UK. malwina.naghibi@protexin.com.

3 Protexin, Medical Affairs, Probiotics International Ltd., Lopen Head, Somerset TA13 5JH, UK. davinder.garcha@protexin.com.

Abstract

Irritable bowel syndrome is a highly prevalent gastrointestinal disorder that threatens the quality of life of millions and poses a substantial financial burden on healthcare systems around the world. Intense research into the human microbiome has led to fascinating discoveries which directly and indirectly implicate the diversity and function of this occult organ in irritable bowel syndrome (IBS) pathophysiology. The benefit of manipulating the gastrointestinal microbiota with diet and probiotics to improve symptoms has been demonstrated in a wealth of both animal and human studies. The positive and negative mechanistic roles bacteria play in IBS will be explored and practical probiotic and dietary choices offered.

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