Cell Host Microbe. 2020 May 13;27(5):689-691. doi: 10.1016/j.chom.2020.04.018.

Julia Fritsch ¹, Maria T Abreu ²

Author information

¹Crohn's and Colitis Center, Division of Gastroenterology, Department of Medicine, University of Miami Leonard Miller School of Medicine, Miami, FL, USA.

²Crohn's and Colitis Center, Division of Gastroenterology, Department of Medicine, University of Miami Leonard Miller School of Medicine, Miami, FL, USA. Electronic address: mabreu1@med.miami.edu.

Abstract

In this issue of Cell Host & Microbe, Leonardi et al. demonstrate ulcerative colitis patients with high Candida responded best to fecal microbial transplant (FMT). However, decreased Candida post-treatment was associated with improved disease-suggesting that Candida reductions are associated with less inflammation. Pre-FMT Candida levels may identify FMT responders.