Diagnostics (Basel). 2019 Dec 13;9(4):221. doi: 10.3390/diagnostics9040221.

Hayfa Sharif ^1 2 3, David Devadason ⁴, Nichola Abrehart ^1 3, Rebecca Stevenson ⁵, Luca Marciani ^1 3 5

Author information

• ¹Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham NG7 2UH, UK.
• ²Amiri Hospital, Ministry of Health, Civil Service Commission, Kuwait City 12025, Kuwait.
• ³National Institute for Health Research (NIHR), Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK.
• ⁴Nottingham Children's Hospital, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, UK.
• ⁵Precision Imaging Beacon, University of Nottingham, Nottingham NG7 2UH, UK.

Abstract

Background: functional gastrointestinal disorders (FGID) are common conditions in children and adults, often associated with abnormalities of whole gut transit. Currently, transit tests can be performed using several imaging methods, including tracking of radiopaque markers, gamma scintigraphy with the use of radioisotopes, magnetic tracking methods, tracking of movement of wireless motility capsules, and emerging magnetic resonance imaging (MRI) approaches.

Objectives: to review recent literature on diagnostic imaging techniques used to investigate whole gut transit in FGIDs.

Methods: a systematic review was carried out. The different techniques are described briefly, with particular emphasis on contemporary literature and new developments, particularly in the field of MRI.

Conclusions: emerging MRI capsule marker methods are promising new tools to study whole gut transit in FGIDs.