Acta Paediatr. 2021 Jul;110(7):2233-2239. doi: 10.1111/apa.15787. Epub 2021 Feb 11.

Adi Anafy ^1 2, Shlomi Cohen ^1 2, Amir Ben Tov ^1 2, Achiya Amir ^1 2, Yael Weintraub ^1 2, Hadar Moran-Lev ^1 2, Margalit Dali Levy ^1 2, Maayan Ankona Bussel ^1 2, Anat Yerushalmy Feler ^1 2

Author information

• ¹Pediatric Gastroenterology Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
• ²Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Abstract

Aim: More normal weight and overweight children are currently diagnosed with celiac disease (CD). We aimed to describe the relation between body mass index (BMI) and the clinical characteristics of paediatric CD and to determine the effect of a gluten-free diet (GFD) on BMI.

Methods: Data on all children diagnosed with CD during 7/2010-7/2019 with documented anthropometric data at diagnosis were retrospectively analysed. The children were divided into three groups according to BMI status at diagnosis: underweight, normal weight and overweight (BMIs <5%, 5%-85% and >85%, respectively).

Results: Of the 236 children [median age 7.87 (4.91-11) years] included in the study, 24 (10.1%) were underweight at diagnosis and 32 (13.6%) were overweight. Diarrhoea as the presenting symptom was significantly more common in the overweight group (p = 0.012), while short stature was more common in the underweight group (p = 0.002). Following a GFD had no significant effect on the children's BMI during a median follow-up of 15.7 (0-85) months, but there was a significant shift of patients between the BMI categories (p < 0.001).

Conclusion: Although a shift of patients between the BMI categories was observed, following a GFD did not significantly affect the overall BMI in children with CD.